FOA (2023): Sugar beet production. Unter Mitarbeit von Food and Agriculture Organization of the United Nations. Hg. v. Food and Agriculture Organization of the United Nations. https://ourworldindata.org/grapher/sugar-beet-production.
Usmani Z, Sharma M, Diwan D, Tripathi M, Whale E, Jayakody LN, et al. Valorization of sugar beet pulp to value-added products: a review. Biores Technol. 2022;346:126580. https://doi.org/10.1016/j.biortech.2021.126580.
Tomaszewska J, Bieliński D, Binczarski M, Berlowska J, Dziugan P, Piotrowski J, et al. Products of sugar beet processing as raw materials for chemicals and biodegradable polymers. Royal Soc Chem Adv. 2018;8(6):3161–77. https://doi.org/10.1039/C7RA12782K.
Duraisam R, Salelgn K, Berekete AK. Production of beet sugar and bio-ethanol from sugar beet and it bagasse: A review. Int J Eng Trends Technol. 2017;43(4):222–33. https://doi.org/10.14445/22315381/ijett-v43p237.
Kühnel S, Schols HA, Gruppen H. Aiming for the complete utilization of sugar-beet pulp: examination of the effects of mild acid and hydrothermal pretreatment followed by enzymatic digestion. Biotechnol Biofuels. 2011;4(1):S14. https://doi.org/10.1186/1754-6834-4-14.
Amoah J, Kahar P, Ogino C, Kondo A. Bioenergy and biorefinery: feedstock, biotechnological conversion, and products. Biotechnol J. 2019;14(6):e1800494. https://doi.org/10.1002/biot.201800494.
Kumar K, Singh E, Shrivastava S. Microbial xylitol production. Appl Microbiol Biotechnol. 2022;106(3):971–9. https://doi.org/10.1007/s00253-022-11793-6.
Mussatto, Solange Inês (2012): Application of xylitol in food formulations and benefits for health. In: Silvio Silvério Da Silva und Anuj Kumar Chandel (Hg.): D-Xylitol. Fermentative production, application and commercialization. Berlin, Heidelberg: Springer Berlin Heidelberg; Imprint; Springer, S. 309–323. Online verfügbar unter https://doi.org/10.1007/978-3-642-31887-0_14.
Gasmi Benahmed A, Gasmi A, Arshad M, Shanaida M, Lysiuk R, Peana M, et al. Health benefits of xylitol. Appl Microbiol Biotechnol. 2020;104(17):7225–37. https://doi.org/10.1007/s00253-020-10708-7.
Mathur S, Kumar D, Kumar V, Dantas A, Verma R, Kuca K. Xylitol: production strategies with emphasis on biotechnological approach, scale up, and market trends. Sustain Chem Pharm. 2023;35:101203. https://doi.org/10.1016/j.scp.2023.101203.
Felipe Hernández-Pérez A, de Arruda PV, Sene L, da Silva SS, Kumar Chandel A, de Almeida Felipe MD. Xylitol bioproduction: state-of-the-art, industrial paradigm shift, and opportunities for integrated biorefineries. Critic Rev Biotechnol. 2019;39(7):924–43. https://doi.org/10.1080/07388551.2019.1640658.
Arcaño YD, García OD, Mandelli D, Carvalho WA, Pontes LA. Xylitol: a review on the progress and challenges of its production by chemical route. Catal Today. 2020;344:2–14. https://doi.org/10.1016/j.cattod.2018.07.060.
Hou-Rui Z (2012): Key drivers influencing the large scale production of xylitol. In: Silvio Silvério Da Silva und Anuj Kumar Chandel (Hg.): D-Xylitol. Fermentative production, application and commercialization. Berlin, Heidelberg: Springer Berlin Heidelberg; Imprint; Springer, S. 267–289. https://doi.org/10.1007/978-3-642-31887-0_12.
Regmi P, Knesebeck M, Boles E, Weuster-Botz D, Oreb M. A comparative analysis of NADPH supply strategies in Saccharomyces cerevisiae: production of d-xylitol from d-xylose as a case study. Metabol Eng Commun. 2024;19:e00245. https://doi.org/10.1016/j.mec.2024.e00245.
Hong Y, Dashtban M, Kepka G, Chen S, Qin W. Overexpression of D-xylose reductase (xyl1) gene and antisense inhibition of D-xylulokinase (xyiH) gene increase xylitol production in Trichoderma reesei. Biomed J Res Int. 2014. https://doi.org/10.1155/2014/169705.
Mahmud A, Hattori K, Hongwen C, Kitamoto N, Suzuki T, Nakamura K, Takamizawa K. Xylitol production by NAD(+)-dependent xylitol dehydrogenase (xdhA)- and l-arabitol-4-dehydrogenase (ladA)-disrupted mutants of Aspergillus oryzae. J Biosci Bioeng. 2013;115(4):353–9. https://doi.org/10.1016/j.jbiosc.2012.10.017.
Mäkelä MR, Donofrio N, de Vries RP. Plant biomass degradation by fungi. Fungal Genet Biol. 2014. https://doi.org/10.1016/j.fgb.2014.08.010.
Baker SE. Aspergillus niger genomics: past, present and into the future. J Med Mycol. 2006;44(1):S17-21. https://doi.org/10.1080/13693780600921037.
Meyer V. Metabolic engineering of filamentous fungi. In: Meyer V, editor. Metabolic engineering. Hoboken: John Wiley & Sons, Ltd; 2021.
Chroumpi T, Peng M, Markillie LM, Mitchell HD, Nicora CD, Hutchinson CM, Chelsea M, et al. Re-routing of sugar catabolism provides a better insight into fungal flexibility in using plant biomass-derived monomers as substrates. Front Bioeng Biotechnol. 2021;9:644216. https://doi.org/10.3389/fbioe.2021.644216.
Meng J, Chroumpi T, Mäkelä MR, de Vries RP. Xylitol production from plant biomass by Aspergillus niger through metabolic engineering. Biores Technol. 2022;344:126199. https://doi.org/10.1016/j.biortech.2021.126199.
Witteveen CF, Busink R, Van de Vondervoort P, Dijkema C, Swart K, Visser J. L-arabinose and D-xylose catabolism in Aspergillus niger. Microbiology. 1989;135(8):2163–71. https://doi.org/10.1099/00221287-135-8-2163.
Arentshorst M, Ram AF, Meyer V. Using non-homologous end-joining-deficient strains for functional gene analyses in filamentous fungi. Methods Mol Biol. 2012;835:133–50. https://doi.org/10.1007/978-1-61779-501-5_9.
Sambrook J, Russell DW. Molecular cloning: a laboratory manual. 3rd edition (Vol. 1). 2021.
Tamás MJ, Karlgren S, Bill RM, Hedfalk K, Allegri L, Ferreira M, et al. A short regulatory domain restricts glycerol transport through yeast Fps1p. J Biol Chem. 2003;278(8):6337–45. https://doi.org/10.1074/jbc.M209792200.
Blumhoff M, Steiger MG, Marx H, Mattanovich D, Sauer M. Six novel constitutive promoters for metabolic engineering of Aspergillus niger. Appl Microbiol Biotechnol. 2013;97(1):259–67. https://doi.org/10.1007/s00253-012-4207-9.
Lu Y, Zheng X, Wang Y, Zhang L, Wang L, Lei Y, et al. Evaluation of Aspergillus niger six constitutive strong promoters by fluorescent-auxotrophic selection coupled with flow cytometry: a case for citric acid production. J Fungi. 2022. https://doi.org/10.3390/jof8060568.
Punt PJ, Dingemanse MA, Kuyvenhoven A, Soede RD, Pouwels PH, van den Hondel CA. Functional elements in the promoter region of the Aspergillus nidulans gpdA gene encoding glyceraldehyde-3-phosphate dehydrogenase. Gene. 1990;93(1):101–9. https://doi.org/10.1016/0378-1119(90)90142-e.
Cesbron F, Brunner M, Diernfellner AC. Light-dependent and circadian transcription dynamics in vivo recorded with a destabilized luciferase reporter in Neurospora. Public LibSci One. 2013;8(12):e83660.
Leskinen P, Virta M, Karp M. One-step measurement of firefly luciferase activity in yeast. Yeast. 2003;20(13):1109–13. https://doi.org/10.1002/yea.1024.
Gooch VD, Mehra A, Larrondo LF, Fox J, Touroutoutoudis M, Loros JJ, Dunlap JC. Fully codon-optimized luciferase uncovers novel temperature characteristics of the Neurospora clock. Eukaryot Cell. 2008;7(1):28–37. https://doi.org/10.1128/EC.00257-07.
Lee ME, DeLoache WC, Cervantes B, Dueber JE. A highly characterized yeast toolkit for modular, multipart assembly. Am Chem Soc Syn Biol. 2015;4(9):975–86. https://doi.org/10.1021/sb500366v.
Knesebeck M, Schäfer D, Schmitz K, Rüllke M, Benz JP, Weuster-Botz D. Enzymatic one-pot hydrolysis of extracted sugar beet press pulp after solid-state Fermentation with an Engineered Aspergillus niger Strain. Fermentation. 2023;9(7):582. https://doi.org/10.3390/fermentation9070582.
Leynaud-Kieffer LM, Curran SC, Kim I, Magnuson JK, Gladden JM, Baker SE, Simmons BA. A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable. Pub Lib Sci One. 2019;14(1):e0210243. https://doi.org/10.1371/journal.pone.0210243.
Rüllke M, Meyer F, Schmitz K, Blase H, Tamayo E, Benz JP. A novel luciferase-based reporter tool to monitor the dynamics of carbon catabolite repression in filamentous fungi. Microbial Biotechnol. 2024. https://doi.org/10.1111/1751-7915.70012.
Niu J, Arentshorst M, Seelinger F, Ram AF, Ouedraogo JP. A set of isogenic auxotrophic strains for constructing multiple gene deletion mutants and parasexual crossings in Aspergillus niger. Archiv Microbiol. 2016;198(9):861–8. https://doi.org/10.1007/s00203-016-1240-6.
Meyer V, Arentshorst M, El-Ghezal A, Drews AC, Kooistra R, van den Hondel CA, Ram AF. Highly efficient gene targeting in the Aspergillus niger kusA mutant. J Biotechnol. 2007;128(4):770–5. https://doi.org/10.1016/j.jbiotec.2006.12.021.
Meyer V, Wu B, Ram AF. Aspergillus as a multi-purpose cell factory: current status and perspectives. Biotechnol Lett. 2011;33(3):469–76. https://doi.org/10.1007/s10529-010-0473-8.
Tamás MJ, Luyten K, Sutherland FC, Hernandez A, Albertyn J, Valadi H, et al. Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation. Mol Microbiol. 1999;31(4):1087–104. https://doi.org/10.1046/j.1365-2958.1999.01248.x.
Wei N, Xu H, Kim SR, Jin YS. Deletion of FPS1, encoding aquaglyceroporin Fps1p, improves xylose fermentation by engineered Saccharomyces cerevisiae. Appl Environ Microbiol. 2013;79(10):3193–201. https://doi.org/10.1128/AEM.00490-13.
Dunayevich P, Baltanás R, Clemente JA, Couto A, Sapochnik D, Vasen G, Colman-Lerner A. Heat-stress triggers MAPK crosstalk to turn on the hyperosmotic response pathway. Sci Rep. 2018;8(1):15168. https://doi.org/10.1038/s41598-018-33203-6.
Zhang H, Yan JN, Zhang H, Liu TQ, Xu Y, Zhang YY, Li J. Effect of gpd box copy numbers in the gpdA promoter of Aspergillus nidulans on its transcription efficiency in Aspergillus niger. Fed Eur Biochem Soc Lett. 2018. https://doi.org/10.1093/femsle/fny154.
Adnan M, Zheng W, Islam W, Arif M, Abubakar YS, Wang Z, Lu G. Carbon catabolite repression in filamentous fungi. Int J Mol Sci. 2017. https://doi.org/10.3390/ijms19010048.
Gancedo JM. Yeast carbon catabolite repression. Microbiol Mol Biol Rev. 1998;62(2):334–61. https://doi.org/10.1128/MMBR.62.2.334-361.1998.
Ruijter GJ, Visser J. Carbon repression in Aspergilli. Fed Eur Biochem Soc Lett. 1997;151(2):103–14. https://doi.org/10.1111/j.1574-6968.1997.tb12557.x.
Dowzer CE, Kelly JM. Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon catabolite repression. Curr Genet. 1989;15(6):457–9. https://doi.org/10.1007/BF00376804.
Mäkelä MR, Aguilar-Pontes MV, van Rossen-Uffink D, Peng M, de Vries RP. The fungus Aspergillus niger consumes sugars in a sequential manner that is not mediated by the carbon catabolite repressor CreA. Sci Rep. 2018;8(1):6655. https://doi.org/10.1038/s41598-018-25152-x.
Ruijter GJ, Vanhanen SA, Gielkens MM, van de Vondervoort PJ, Visser J. Isolation of Aspergillus niger creA mutants and effects of the mutations on expression of arabinases and L-arabinose catabolic enzymes. Microbiology. 1997;143(Pt9):2991–8. https://doi.org/10.1099/00221287-143-9-2991.
Schäfer D, Schmitz K, Weuster-Botz D, Benz JP. Comparative evaluation of Aspergillus niger strains for endogenous pectin-depolymerization capacity and suitability for D-galacturonic acid production. Bioproc Biosyst Eng. 2020;43(9):1549–60. https://doi.org/10.1007/s00449-020-02347-z.
Rutten L, Ribot C, Trejo-Aguilar B, Wösten HA, de Vries RP. A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol. Biomed Central Microbiol. 2009;9:166. https://doi.org/10.1186/1471-2180-9-166.
Koivistoinen OM, Richard P, Penttilä M, Ruohonen L, Mojzita D. Sorbitol dehydrogenase of Aspergillus niger, SdhA, is part of the oxido-reductive D-galactose pathway and essential for D-sorbitol catabolism. Fed Eur Biochem Soc Lett. 2012;586(4):378–83. https://doi.org/10.1016/j.febslet.2012.01.004.
Karlgren S, Pettersson N, Nordlander B, Mathai JC, Brodsky JL, Zeidel ML, et al. Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling. J Biol Chem. 2005;280(8):7186–93. https://doi.org/10.1074/jbc.M413210200.
Lee J, Reiter W, Dohnal I, Gregori C, Beese-Sims S, Kuchler K, et al. MAPK Hog1 closes the S cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators. Genes Dev. 2013;27(23):2590–601. https://doi.org/10.1101/gad.229310.113.
De Groot MJ, Van Den Dool C, Wösten HA, Levisson M, VanKuyk PA, Ruijter GJ, De Vries RP. Regulation of pentose catabolic pathway genes of Aspergillus niger. Food Technol Biotechnol. 2007;45(2):134–8.
Mert HH, Dizbay M. The effect of osmotic pressure and salinity of the medium on the growth and sporulation of Aspergillus niger and Paecilomyces lilacinum species. Mycopathologia. 1977;61(2):125–7. https://doi.org/10.1007/BF00443842.
Beever RE, Laracy EP. Osmotic adjustment in the filamentous fungus Aspergillus nidulans. J Bacteriol. 1986;168(3):1358–65. https://doi.org/10.1128/jb.168.3.1358-1365.1986.
Ianutsevich EA, Tereshina VM. Combinatorial impact of osmotic and heat shocks on the composition of membrane lipids and osmolytes in Aspergillus niger. Microbiology. 2019;165(5):554–62. https://doi.org/10.1099/mic.0.000796.
Poulsen RB, Nøhr J, Douthwaite S, Hansen LV, Iversen JJ, Visser J, Ruijter GJ. Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger. Fed Eur Biochem Soc J. 2005;272(6):1313–25. https://doi.org/10.1111/j.1742-4658.2005.04554.x.
Shroff RA, Lockington RA, Kelly JM. Analysis of mutations in the creA gene involved in carbon catabolite repression in Aspergillus nidulans. Can J Microbiol. 1996;42(9):950–9. https://doi.org/10.1139/m96-122.
Saha BC, Kennedy GJ. Production of xylitol from mixed sugars of xylose and arabinose without co-producing arabitol. Biocatal Agricult Biotechnol. 2020;29:101786. https://doi.org/10.1016/j.bcab.2020.101786.
Sakakibara Y, Saha BC, Taylor P. Microbial production of xylitol from L-arabinose by metabolically engineered Escherichia coli. J Biosci Bioeng. 2009;107(5):506–11. https://doi.org/10.1016/j.jbiosc.2008.12.017.
Yoon BH, Jeon WY, Shim WY, Kim JH. L-arabinose pathway engineering for arabitol-free xylitol production in Candida tropicalis. Biotechnol Lett. 2011;33(4):747–53. https://doi.org/10.1007/s10529-010-0487-2.
Add Comment