Scientific Papers

Low selection of HIV PrEP refills at private pharmacies among clients who initiated PrEP at public clinics: findings from a mixed-methods study in Kenya | BMC Health Services Research


  • Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367(5):399–410.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, Segolodi TM, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423–34.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Galvani AP, Pandey A, Fitzpatrick MC, Medlock J, Gray GE. Defining control of HIV epidemics. The lancet HIV. 2018;5(11):e667–70.

    Article 
    PubMed 

    Google Scholar
     

  • Joint United Nations Programme on HIV/AIDS. In danger: UNAIDS global AIDS update 2022. 2022.


    Google Scholar
     

  • Kyongo J, Kiragu M, Karuga R, Ochieng C, Ngunjiri A, Wachihi C, et al., editors. How long will they take it? Oral pre-exposure prophylaxis (PrEP) retention for female sex workers, men who have sex with men and young women in a demonstration project in Kenya. Oral abstract at the 22nd International AIDS Conference, Amsterdam, the Netherlands. 2018. Abstract WEAE0403.

  • Pillay D, Jenkins S, Murire M, Stankevitz K, Subedar H, Mullick S, editors. Factors influencing initiation, continuation & discontinuation of oral PrEP at selected facilities in South Africa. Oral abstract at the 22nd International AIDS Conference, Amsterdam, the Netherlands. 2018. Abstract WEAE0401.

  • Gombe MM, Mangwendeza Y, Ncube G, Zwangobani N, Prust M, Cakouros B, et al. Integrating oral HIV pre-exposure prophylaxis (PrEP) in a public family planning facility and youth center to inform national roll out in Zimbabwe. Oral abstract at the 22nd International AIDS Conference, Amsterdam, the Netherlands. 2018. Abstract TUAC0307LB.

  • Mugwanya K, Pintye J, Kinuthia J, Abuna F, Lagat H, Serede M, et al., editors. Uptake of PrEP within clinics providing integrated family planning and PrEP services: results from a large implementation program in Kenya. Oral abstract at the 22nd International AIDS Conference, Amsterdam, the Netherlands. 2018. Abstract TUAC0304.

  • Mack N, Odhiambo J, Wong CM, Agot K. Barriers and facilitators to pre-exposure prophylaxis (PrEP) eligibility screening and ongoing HIV testing among target populations in Bondo and Rarieda, Kenya: results of a consultation with community stakeholders. BMC Health Serv Res. 2014;14(1):1–12.

    Article 

    Google Scholar
     

  • Patel RC, Stanford-Moore G, Odoyo J, Pyra M, Wakhungu I, Anand K, et al. “Since both of us are using antiretrovirals, we have been supportive to each other”: facilitators and barriers of pre‐exposure prophylaxis use in heterosexual HIV serodiscordant couples in Kisumu, Kenya. J Int AIDS Soc. 2016;19(1):21134.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Peterson J, Brunie A, Diop I, Diop S, Stanback J, Chin-Quee DS. Over the counter: the potential for easing pharmacy provision of family planning in urban Senegal. Gates Open Res. 2018;2:29.

  • Roche SD, Wairimu N, Mogere P, Kamolloh K, Odoyo J, Kwena ZA, et al. Acceptability and feasibility of pharmacy-based delivery of pre-exposure prophylaxis in Kenya: a qualitative study of client and provider perspectives. AIDS Behav. 2021;1–2.

  • Kwena Z, Sharma A, Muga C, Wamae N, Bukusi E. Management of simulated patients with sexually transmitted infections by staff of retail pharmacies in Kibera slums of Nairobi. East Afr Med J. 2008;85(9):419–24.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bigogo G, Audi A, Aura B, et al. Health-seeking patterns among participants of population-based morbidity surveillance in rural western Kenya: implications for calculating disease rates. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2010;14(11):e967–73.

    PubMed 

    Google Scholar
     

  • Abuya TO, Mutemi W, Karisa B, Ochola SA, Fegan G, Marsh V. Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions. Malar J. 2007;6:57-.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Onwujekwe O, Hanson K, Uzochukwu B. Do poor people use poor quality providers? Evidence from the treatment of presumptive malaria in Nigeria. Tropical Med Int Health. 2011;16(9):1087–98.

    Article 

    Google Scholar
     

  • Ortblad KF, Mogere P, Bukusi E, Ngure K, Baeten JM. Pharmacy delivery to expand the reach of PrEP in Africa. Journal of the International AIDS Society. 2020;23(9):e25619.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Roche S, Omollo O, Mogere P, Asewe M, Gakuo S, Banerjee P, et al. Pharmacy-based PrEP delivery in Kenya: findings from a pilot study extension​. Themed discussion at CROI 2023: 30th Conference on Retroviruses and Opportunistic Infections, Seattle, USA. 2023. Abstract 978.

  • Ortblad KF MP, Omollo V, Kuo A, Asewe M, Gauko S, Roche S, Mugambi M, Mugambi ML, Stergachis A, Odoyo J, Bukusi E, Ngure K, Baeten JM. Stand-alone model for delivery of oral HIV pre-exposure prophylaxis in Kenya: a single-arm, prospective pilot evaluation. J Int AIDS Soc. 2023;26(6):e26131.

  • Pintye J, Odoyo J, Nyerere B, Achieng P, Araka E, Omondi C, et al. Nurse-facilitated preexposure prophylaxis delivery for adolescent girls and young women seeking contraception at retail pharmacies in Kisumu, Kenya. AIDS (London, England). 2023;37(4):617.

    Article 
    PubMed 

    Google Scholar
     

  • Irungu EM, Mugwanya KK, Mugo NR, Bukusi EA, Donnell D, Odoyo J, et al. Integration of pre-exposure prophylaxis services into public HIV care clinics in Kenya: a pragmatic stepped-wedge randomised trial. Lancet Glob Health. 2021;9(12):e1730–9.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Guest G, Fleming P. Mixed methods research. Public health research methods. 2015;5:581–614.

    Article 

    Google Scholar
     

  • National AIDS & STI Control Program MoH, Kenya. Kenya HIV Estimates 2018. 2018.


    Google Scholar
     

  • Pharmacy and Poisons Board: Facilities register [Internet]. Ministry of Health, Nairobi, Kenya. 2024 . Available from: https://practice.pharmacyboardkenya.org/LicenseStatus?register=facilities&ftype=retail2023. Accessed 1 Oct 2023.

  • Heffron R, Ngure K, Odoyo J, Bulya N, Tindimwebwa E, Hong T, et al. Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa. Gates open research. 2017;1:3.

    Article 
    PubMed 

    Google Scholar
     

  • Roche SD, Barnabee G, Omollo V, Mogaka F, Odoyo J, Bukusi EA, et al. Implementation strategies for integrating pre-exposure prophylaxis for HIV prevention and family planning services for adolescent girls and young women in Kenya: a qualitative study. BMC Health Serv Res. 2022;22(1):1–15.

    Article 

    Google Scholar
     

  • Wanga V, Omollo V, Bukusi EA, Odoyo JB, Morton JF, Kidoguchi L, et al. Uptake and impact of facility-based HIV self-testing on PrEP delivery: a pilot study among young women in Kisumu, Kenya. Journal of the International AIDS Society. 2020;23(8):e25561–e.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Haberer JE, Mugo N, Bukusi EA, Ngure K, Kiptinness C, Oware K, et al. Understanding pre-exposure prophylaxis adherence in young women in Kenya. J Acquir Immune Defic Syndr. 2022;89(3):251–60.

    Article 
    PubMed 

    Google Scholar
     

  • National AIDS & STI Control Program MoH, Kenya. Guidelines on use of antiretroviral drugs for treating and preventing HIV infection in Kenya. 2018.


    Google Scholar
     

  • Ortblad KF, Mogere P, Roche S, Kamolloh K, Odoyo J, Irungu E, et al. Design of a care pathway for pharmacy-based PrEP delivery in Kenya: results from a collaborative stakeholder consultation. BMC Health Services Research. 2020;20:1034.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wilson IB, Yunfeng T, Padilla M, Rogers WH, Linda B. Performance of a short, self-report adherence scale in a probability sample of persons using HIV antiretroviral therapy in the United States. AIDS (London, England). 2020;34(15):2239.

    Article 
    PubMed 

    Google Scholar
     

  • Sekhon M, Cartwright M, Francis JJ. Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework. BMC Health Serv Res. 2017;17(1):88.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ortblad KF, Sekhon M, Wang L, Roth S, van der Straten A, Simoni JM, et al. Acceptability assessment in HIV prevention and treatment intervention and service delivery research: a systematic review and qualitative analysis. AIDS Behav. 2023;27(2):600–17.

    Article 
    PubMed 

    Google Scholar
     

  • Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, et al. Psychometric assessment of three newly developed implementation outcome measures. Implementation science. 2017;12(1):108.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ortblad KF, Mogere P, Omollo V, Kuo AP, Asewe M, Gakuo S, et al. Stand‐alone model for delivery of oral HIV pre‐exposure prophylaxis in Kenya: a single‐arm, prospective pilot evaluation. J Int AIDS Soc. 2023;26(6):e26131.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mason M. Sample size and saturation in PhD studies using qualitative interviews. Forum qual. 2010;11(3).

  • Vaismoradi M, Turunen H, Bondas T. Content analysis and thematic analysis: Implications for conducting a qualitative descriptive study. Nurs Health Sci. 2013;15(3):398–405.

    Article 
    PubMed 

    Google Scholar
     

  • Irungu EM, Mugwanya KK, Mugo NR, Bukusi EA, Ngure K, Odoyo J, et al. Rapid scale-up of PrEP for HIV serodiscordant couples in HIV care clinics in Kenya. Topics in Antiviral Medicine. 2018;26:483s–s.


    Google Scholar
     

  • Mugwanya KK, Pintye J, Kinuthia J, Abuna F, Lagat H, Begnel ER, et al. Integrating preexposure prophylaxis delivery in routine family planning clinics: a feasibility programmatic evaluation in Kenya. PLoS Med. 2019;16(9):e1002885.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Pintye J, Kinuthia J, Roberts DA, Wagner AD, Mugwanya K, Abuna F, et al. Integration of PrEP services into routine antenatal and postnatal care: experiences from an implementation program in Western Kenya. Journal of acquired immune deficiency syndromes. 2018;79(5):590.

    Article 
    PubMed 

    Google Scholar
     

  • Ngure K, Mugo NR, Bukusi EA, Kiptinness C, Oware K, Gakuo S, et al. Pills, injections, rings, or implants? PrEP formulation preferences of PrEP-experienced African women for HIV prevention. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2021;88(4):e30–2.

    Article 
    PubMed 

    Google Scholar
     



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