Within the first few days of contact, CCHF can induce critical damage to the infected individual leading to many serious and possibly fatal outcomes. The common initial symptoms of this illness present as fever, headaches, myalgia, fatigue, and gastrointestinal distress. In severe cases, the manifestations may progress to hemorrhages including gingival and petechial hemorrhages, epistaxis, ecchymoses, and other forms of extensive bleeding . Currently, the available diagnostic tests for CCHF include a reverse transcription–polymerase chain reaction (RT–PCR) assay, enzyme linked immunosorbent assay (ELISA), detection of antigen-specific antibodies, or through isolating the virus on cell culture . The primary treatment for CCHF is supportive care and management of symptoms, however in some cases oral and intravenous administration of ribavirin, an antiviral drug, has also shown benefit . Two vaccines against the virus have also been developed but neither of them has been approved for administration as of yet .
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