Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO. The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod. 2016;31:2841–55.
Gibson-Helm ME, Teede HJ, Dunaif A, Dokras A. Delayed diagnosis and a lack of information associated with dissatisfaction in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2017;102(2):604–12. https://doi.org/10.1210/jc.2016-2963. PMID:27906550;PMCID:PMC6283441.
Teede HJ, Tay CT, Laven J, Dokras A, Moran LJ, Piltonen T, Costello M, Boivin J, Redman L, Boyle A, Norman R, Mousa A, Joham A. International PCOS network. Fertil Steril. 2023;120(4):767–93.
Deswal R, Narwal V, Dang A, Pundir CS. The prevalence of polycystic ovary syndrome: a brief systematic review. J Hum Reprod Sci. 2020;13:261–71.
Hart R, Doherty DA. The potential implications of a PCOS diagnosis on a woman’s long-term health using data linkage. J Clin Endocrinol Metab. 2015;100(3):911–9. https://doi.org/10.1210/jc.2014-3886. Epub 2014 Dec 22. Erratum in: J Clin Endocrinol Metab. 2015 Jun;100(6):2502. PMID: 25532045.
Kiconco S, Tay CT, Rassie KL, et al. Natural history of polycystic ovary syndrome: a systematic review of cardiometabolic outcomes from longitudinal cohort studies. Clin Endocrinol (Oxf). 2022;96:475–98.
Pinola P, Puukka K, Piltonen TT, Puurunen J, Vanky E, Sundström-Poromaa I, Stener-Victorin E, Hirschberg AL, Ravn P, Andersen S, et al. Normo- and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life. Fertil Steril. 2017;107:e2788-2795.
Dokras A, Stener-Victorin E, Yildiz BO, Li R, Ottey S, Shah D, Epperson N, Teede H. Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome. Fertil Steril. 2018;109:888–99.
Cooney LG, Dokras A. Beyond fertility: polycystic ovary syndrome and long-term health. Fertil Steril. 2018;110(5):794–809. https://doi.org/10.1016/j.fertnstert.2018.08.021. PMID: 30316414.
Rubin KH, Glintborg D, Nybo M, et al. Development and risk factors of type 2 diabetes in a nationwide population of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2017;102:3848–57.
Glintborg D, Rubin KH, Nybo M, Abrahamsen B, Andersen M. Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome. Cardiovasc Diabetol. 2018;17(1):37. https://doi.org/10.1186/s12933-018-0680-5. PMID:29519249;PMCID:PMC5844097.
Berni TR, Morgan CL, Rees DA. Women with polycystic ovary syndrome have an increased risk of major cardiovascular events: a population study. J Clin Endocrinol Metab. 2021;106(9):e3369–80. https://doi.org/10.1210/clinem/dgab392. PMID:34061968;PMCID:PMC8372630.
Wekker V, van Dammen L, Koning A, Heida KY, Painter RC, Limpens J, Laven JSE, van RoetersLennep JE, Roseboom TJ, Hoek A. Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis. Hum Reprod Update. 2020;26(6):942–60. https://doi.org/10.1093/humupd/dmaa029. PMID: 32995872; PMCID: PMC7600286.
Riestenberg C, Jagasia A, Markovic D, et al. Health care-related economic burden of polycystic ovary syndrome in the United States: pregnancy-related and long-term health consequences. J Clin Endocrinol Metab. 2022;107:575–85.
Coffey S, Bano G, Mason HD. Health-related quality of life in women with polycystic ovary syndrome: a comparison with the general population using the Polycystic Ovary Syndrome Questionnaire (PCOSQ) and the Short Form-36 (SF-36). Gynecol Endocrinol. 2006;22(2):80–6. https://doi.org/10.1080/09513590600604541. PMID: 16603432.
Himelein MJ, Thatcher SS. Depression and body image among women with polycystic ovary syndrome. J Health Psychol. 2006;11:613–25.
Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Kazemnejad A, Faghihzadeh S. Body image satisfaction and self-esteem status among the patients with polycystic ovary syndrome. Int J Reprod BioMed. 2013;11:829–36.
Tay CT, Teede HJ, Hill B, Loxton D, Joham AE. Increased prevalence of eating disorders, low self-esteem, and psychological distress in women with polycystic ovary syndrome: a community-based cohort study. Fertil Steril. 2019;112:353–61.
Martin ML, Halling K, Eek D, Krohe M, Paty J. Understanding polycystic ovary syndrome from the patient 368 perspective: a concept elicitation patient interview study. Health Qual Life Outcomes. 2017;15(162):369. https://doi.org/10.1186/s12955-017-0736-3. Accessed 13 Apr 2021.
Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016;2:16057. https://doi.org/10.1038/nrdp.2016.57. PMID: 27510637.
Actkins KV, Singh K, Hucks D, Velez Edwards DR, Aldrich M, Cha J, Wellons M, Davis LK. Characterizing the clinical and genetic spectrum of polycystic ovary syndrome in electronic health records. J Clin Endocrinol Metab. 2021;106(1):153–67. https://doi.org/10.1210/clinem/dgaa675. PMID: 32961557.
Bonny AE, Appelbaum H, Connor EL, Cromer B, DiVasta A, Gomez-Lobo V, Harel Z, Huppert J, Sucato G, NASPAG Research Committee. Clinical variability in approaches to polycystic ovary syndrome. J Pediatr Adolesc Gynecol. 2012;25(4):259–61. https://doi.org/10.1016/j.jpag.2012.03.004. PMID: 22840936.
Witchel SF, Oberfield S, Rosenfield RL, Codner E, Bonny A, Ibáñez L, Pena A, Horikawa R, Gomez-Lobo V, Joel D, Tfayli H, Arslanian S, Dabadghao P, Garcia Rudaz C, Lee PA. The diagnosis of polycystic ovary syndrome during adolescence. Horm Res Paediatr. 2015. https://doi.org/10.1159/000375530. Online ahead of print. PMID: 25833060.
West S, Lashen H, Bloigu A, Franks S, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, Morin-Papunen L. Irregular menstruation and hyperandrogenaemia in adolescence are associated with polycystic ovary syndrome and infertility in later life: Northern Finland Birth Cohort 1986 study. Hum Reprod. 2014;29(10):2339–51. https://doi.org/10.1093/humrep/deu200. Epub 2014 Aug 1. PMID: 25085801; PMCID: PMC4164150.
Bellver J, Rodríguez-Tabernero L, Robles A, Muñoz E, Martínez F, Landeras J, García-Velasco J, Fontes J, Álvarez M, Álvarez C, Acevedo B, Group of interest in Reproductive Endocrinology (GIER) of the Spanish Fertility Society (SEF). Polycystic ovary syndrome throughout a woman’s life. J Assist Reprod Genet. 2018;35(1):25–39. https://doi.org/10.1007/s10815-017-1047-7. Epub 2017 Sep 27. PMID: 28951977; PMCID: PMC5758469.
Belan M, Harnois-Leblanc S, Laferrère B, Baillargeon JP. Optimizing reproductive health in women with obesity and infertility. CMAJ. 2018;190:E742-745.
Azziz R. Polycystic ovary syndrome. Obstet Gynecol. 2018;132(2):321–36. https://doi.org/10.1097/AOG.0000000000002698. PMID: 29995717.
Hoyos LR, Putra M, Armstrong AA, Cheng CY, Riestenberg CK, Schooler TA, Dumesic DA. Measures of patient dissatisfaction with health care in polycystic ovary syndrome: retrospective analysis. J Med Internet Res. 2020;22(4):e16541. https://doi.org/10.2196/16541. PMID:32314967;PMCID:PMC7201322.
Pirotta S, Joham A, Grieger JA, Tay CT, Bahri-Khomami M, Lujan M, Lim SS, Moran LJ. Obesity and the risk of infertility, gestational diabetes, and type 2 diabetes in polycystic ovary syndrome. Semin Reprod Med. 2020;38(6):342–51. https://doi.org/10.1055/s-0041-1726866. Epub 2021 Apr 19 PMID: 33873233.
Gibson-Helm ME, Lucus IM, Boyle JA, Teede HJ. Women’s experiences of polycystic ovary syndrome diagnosis. Fam Pract. 2014;31(5):545–9. https://doi.org/10.1093/fampra/cmu028.
Tomlinson J, Pinkney J, Adams L, Stenhouse E, Bendall A, Corrigan O, Letherby G. The diagnosis and lived experience of polycystic ovary syndrome: a qualitative study. J Adv Nurs. 2017;73(10):2318–26. https://doi.org/10.1111/jan.13300. Epub 2017 May 15 PMID: 28329428.
Hoeger KM, Dokras A, Piltonen T. Update on PCOS: consequences, challenges, and guiding treatment. J Clin Endocrinol Metab. 2021;106(3):e1071–83. https://doi.org/10.1210/clinem/dgaa839. PMID: 33211867.
Kaur I, Suri V, Rana SV, Singh A. Treatment pathways traversed by polycystic ovary syndrome (PCOS) patients: a mixed-method study. PLOS ONE. Published: August 9, 2021 https://doi.org/10.1371/journal.pone.0255830.
Ismayilova M, Yaya S. “I felt like she didn’t take me seriously”: a multi-methods study examining patient satisfaction and experiences with polycystic ovary syndrome (PCOS) in Canada. BMC Womens Health. 2022;22:47. https://doi.org/10.1186/s12905-022-01630-3.
Presswala B, De Souza LR. The diagnostic experience of polycystic ovary syndrome: a scoping review of patient perspectives. Patient Educ Couns. 2023;113:107771. https://doi.org/10.1016/j.pec.2023.107771. Epub 2023 Apr 23 PMID: 37141692.
Crete J, Adamshick P. Managing polycystic ovary syndrome: what our patients are telling Us. J Holist Nurs. 2011;29(4):256–66. https://doi.org/10.1177/0898010111398660.
Fernandez RC, Moore VM, Rumbold AR, Whitrow MJ, Avery JC, Davies MJ. Diagnosis delayed: health profile differences between women with undiagnosed polycystic ovary syndrome and those with a clinical diagnosis by age 35 years. Hum Reprod. 2021;36(8):2275–84. https://doi.org/10.1093/humrep/deab101.
Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018;110(3):364–79. https://doi.org/10.1016/j.fertnstert.2018.05.004. Epub 2018 Jul 19. PMID: 30033227; PMCID: PMC6939856.
Eysenbach G. Improving the quality of web surveys: the checklist for reporting results of internet e-surveys (CHERRIES). J Med Internet Res. 2004;6(3):e34. https://doi.org/10.2196/jmir.6.3.e34. PMID:15471760.PMCID:PMC1550605.
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap) – A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81.
PCOS Together. 2021. Understanding Health Care in PCOS. https://pcos.together.ualberta.ca/understanding-388health-care-in-pcos/. Accessed 13 Apr 2021.
University of Alberta. 2021. Human Nutrition Research Unit-Current Studies. https://hnru.ualberta.ca/current-390studies/. Accessed 13 Apr 2021.
Alberta SPOR SUPPORT UNIT. 2021. Patient Engagement Platform/Family Registry https://app.betterimpact.com/PublicOrganization/25809ea0-7311-40db-bfac-aaa0e28ba518/1. Accessed 13 Apr 2021.
Bingham AJ, & Witkowsky P. (2022). Deductive and inductive approaches to qualitative data analysis. In C. Vanover, P. Mihas, & J. Saldaña (Eds.), Analyzing and interpreting qualitative data: After the interview (pp. 133-146). SAGE Publications.
Katz A, Enns J, Wong ST, Williamson T, Singer A, McGrail K, Bakal JA, Taylor C, Peterson S. Challenges associated with cross-jurisdictional analyses using administrative health data and primary care electronic medical records in Canada. Int J Popul Data Sci. 2018;3(3):437. https://doi.org/10.23889/ijpds.v3i3.437. PMID:34095523;PMCID:PMC8142948.
Gibson-Helm M, Tassone EC, Teede HJ, Dokras A, Garad R. The needs of women and healthcare providers regarding polycystic ovary syndrome information, resources, and education: a systematic search and narrative review. Semin Reprod Med. 2018;36(1):35–41. https://doi.org/10.1055/s-0038-1668086. Epub 2018 Sep 6 PMID: 30189449.
Soucie K, Samardzic T, Schramer K, Ly C, Katzman R. The diagnostic experiences of women with polycystic ovary syndrome (PCOS) in Ontario, Canada. Qual Health Res. 2021;31(3):523–34. https://doi.org/10.1177/1049732320971235. Epub 2020 Nov 19 PMID: 33213256.
Ismayilova M, Yaya S. ‘I’m usually being my own doctor’: women’s experiences of managing polycystic ovary syndrome in Canada. Interntl Health. 2023;15(1):56–66. https://doi.org/10.1093/inthealth/ihac028.
Chemerinski A, Cooney L, Shah D, Butts S, Gibson-Helm M, Dokras A. Knowledge of PCOS in physicians- in-training: identifying gaps and educational opportunities. Gynecol Endocrinol. 2020;36(10):854–9. https://doi.org/10.1080/09513590.2020.1746761.
Dokras A, Saini S, Gibson-Helm M, Schulkin J, Cooney L, Teede H. Gaps in knowledge among physicians regarding diagnostic criteria and management of polycystic ovary syndrome. Fertil Steril. 2017;107(6):1380-1386.e1. https://doi.org/10.1016/j.fertnstert.2017.04.011. Epub 2017 May 5 PMID: 28483503.
Copp T, Muscat DM, Hersch J, McCaffery KJ, Doust J, Dokras A, Mol BW, Jansen J. The challenges with managing polycystic ovary syndrome: a qualitative study of women’s and clinicians’ experiences. Patient Educ Couns. 2022;105(3):719–25. https://doi.org/10.1016/j.pec.2021.05.038. Epub 2021 May 29 PMID: 34099308.
Copp T, Hersch J, Muscat DM, McCaffery KJ, Doust J, Dokras A, Mol BW, Jansen J. The benefits and harms of receiving a polycystic ovary syndrome diagnosis: a qualitative study of women’s experiences. Hum Reprod Open. 2019;4:hoz026. https://doi.org/10.1093/hropen/hoz026. PMID: 31687475; PMCID: PMC6822814.
Glintborg DRK, Nybo M, Abrahamsen B, Andersen M. Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome. Cardiovasc Diabetol. 2018;17:37.
Dolphin PJ, Rubinstein D. The metabolism of very low density lipoprotein and chylomicrons by purified lipoprotein lipase from rat heart and adipose tissue. Biochem Biophys Res Commun. 1974;57:808–14.
Palomba S, de Wilde MA, Falbo A, Koster MP, La Sala GB, Fauser BC. Pregnancy complications in women with polycystic ovary syndrome. Hum Reprod Update. 2015;21(5):575–92. https://doi.org/10.1093/humupd/dmv029. Epub 2015 Jun 27 PMID: 26117684.
Bahri Khomami M, Joham AE, Boyle JA, Piltonen T, Silagy M, Arora C, Misso ML, Teede H, Moran LJ. Increased maternal pregnancy complications in PCOS appear to be independent of obesity: a systematic review, meta-analysis and meta-regression. Obes Rev. 2019;20:659–74. https://doi.org/10.1111/obr.12829. First published: 23 January 2019.
Hollinrake E, Abreu A, Maifeld M, Van Voorhis BJ, Dokras A. Increased risk of depressive disorders in women with polycystic ovary syndrome. Fertil Steril. 2007;87(6):1369–76 pmid:17397839.
Cooney LG, Lee I, Sammel MD, Dokras A. High prevalence of moderate and severe depressive and anxiety symptoms in polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod. 2017;32(5):1075–91. https://doi.org/10.1093/humrep/dex044.
Hasan M, Sultana S, Sohan M, Parvin S, Rahman MA, Hossain MJ, et al. Prevalence and associated risk factors for mental health problems among patients with polycystic ovary syndrome in Bangladesh: a nationwide cross—Sectional study. PLoS ONE. 2022;17(6):e0270102. https://doi.org/10.1371/journal.pone.0270102.
Chaudhari AP, Mazumdar K, Mehta PD. Anxiety, depression, and quality of life in women with polycystic ovarian syndrome. Indian J Psychol Med. 2018;40(3):239–46. https://doi.org/10.4103/IJPSYM.IJPSYM_561_17. PMID:29875531;PMCID:PMC5968645.
Lee I, Cooney LG, Saini S, Smith ME, Sammel MD, Allison KC, Dokras A. Increased risk of disordered eating in polycystic ovary syndrome. Fertil Steril. 2017;107(3):796–802. https://doi.org/10.1016/j.fertnstert.2016.12.014. Epub 2017 Jan 16 PMID: 28104244.
Pirotta S, Barillaro M, Brennan L, Grassi A, Jeanes YM, Joham AE, Kulkarni J, Couch LM, Lim SS, Moran LJ. Disordered eating behaviours and eating disorders in women in Australia with and without polycystic ovary syndrome: a cross-sectional study. J Clin Med. 2019;8(10):1682. https://doi.org/10.3390/jcm8101682. PMID:31615157;PMCID:PMC6832459.
Burnatowska E, Wikarek A, Oboza P, Ogarek N, Glinianowicz M, Kocelak P, Olszanecka-Glinianowicz M. Emotional eating and binge eating disorders and night eating syndrome in polycystic ovary syndrome-a vicious circle of disease: a systematic review. Nutrients. 2023;15(2):295. https://doi.org/10.3390/nu15020295. PMID:36678165;PMCID:PMC9865055.
Blackshaw LCD, Chhour I, Stepto NK, Lim SS. Barriers and facilitators to the implementation of evidence-based lifestyle management in polycystic ovary syndrome: a narrative review. Med Sci (Basel). 2019;7(7):76. https://doi.org/10.3390/medsci7070076. PMID:31252682;PMCID:PMC6681274.
Shah D, Patil M, National PCOS Working Group. Consensus statement on the use of oral contraceptive pills in polycystic ovarian syndrome women in India. J Hum Reprod Sci. 2018;11(2):96–118. https://doi.org/10.4103/jhrs.JHRS_72_18. PMID: 30158805; PMCID: PMC6094524.
Oguz SH, Yildiz BO. An update on contraception in polycystic ovary syndrome. Endocrinol Metab (Seoul). 2021;36(2):296–311. https://doi.org/10.3803/EnM.2021.958. Epub 2021 Apr 15. PMID: 33853290; PMCID: PMC8090477.
Tang T, Lord JM, Norman RJ, Yasmin E, Balen AH. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database Syst Rev. 2012;5:CD003053.
Bozdag G, Yildiz BO. Interventions for the metabolic dysfunction in polycystic ovary syndrome. Steroids. 2013;78(8):777–81. https://doi.org/10.1016/j.steroids.2013.04.008. ISSN 0039-128X.
Morley LC, Tang T, Yasmin E, Norman RJ, Balen AH. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database Syst Rev. 2017;11:CD003053. https://doi.org/10.1002/14651858.CD003053.pub6.
Zimmerman LD, Setton R, Pereira N, Rosenwaks Z. Contemporary management of polycystic ovarian syndrome. Clin Obstet Gynecol. 2019;62(2):271–81. https://doi.org/10.1097/GRF.0000000000000449.
Humphreys L, Costarelli V. Implementation of dietary and general lifestyle advice among women with polycystic ovarian syndrome. J R Soc Promot Health. 2008;128(4):190–5. https://doi.org/10.1177/1466424008092230. PMID: 18678115.
Moran LJ, Misso ML, Wild RA, Norman RJ. Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update. 2010;16(4):347–63.
Deeks AA, Gibson-Helm ME, Paul E, Teede HJ. Is having polycystic ovary syndrome a predictor of poor psychological function including anxiety and depression? Hum Reprod. 2011;26(6):1399–407.
Ee C, Pirotta S, Mousa A, et al. Providing lifestyle advice to women with PCOS: an overview of practical issues affecting success. BMC Endocr Disord. 2021;21:234. https://doi.org/10.1186/s12902-021-00890-8.
Avery JC, Braunack-Mayer AJ. The information needs of women diagnosed with Polycystic Ovarian Syndrome–implications for treatment and health outcomes. BMC Womens Health. 2007;7:9. https://doi.org/10.1186/1472-6874-7-9. PMID:17578583;PMCID:PMC1906750.
Holbrey S, Coulson NS. A qualitative investigation of the impact of peer-to-peer online support for women living with polycystic ovary syndrome. BMC Womens Health. 2013;13:51. https://doi.org/10.1186/1472-6874-13-51. PMID:24341398;PMCID:PMC3867626.
Rzońca E, Bień A, Wdowiak A, Szymański R, Iwanowicz-Palus G. Determinants of quality of life and satisfaction with life in women with polycystic ovary syndrome. Int J Environ Res Public Health. 2018;15(2):376. https://doi.org/10.3390/ijerph15020376.
Tabassum F, Jyoti C, Sinha HH, Dhar K, Akhtar MS. Impact of polycystic ovary syndrome on quality of life of women in correlation to age, basal metabolic index, education and marriage. PLoS ONE. 2021;16(3):e0247486. https://doi.org/10.1371/journal.pone.0247486.
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