Scientific Papers

Association of triglyceride–glucose index with coronary severity and mortality in patients on dialysis with coronary artery disease | European Journal of Medical Research


  • Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics-2020 update: a report from the American Heart Association. Circulation. 2020;141:e139-596.

    Article 
    PubMed 

    Google Scholar
     

  • Lai AC, Bienstock SW, Sharma R, Skorecki K, Beerkens F, Samtani R, et al. A personalized approach to chronic kidney disease and cardiovascular disease: JACC review topic of the week. J Am Coll Cardiol. 2021;77:1470–9.

    Article 
    PubMed 

    Google Scholar
     

  • Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18:378–95.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Herzog CA, Littrell K, Arko C, Frederick PD, Blaney M. Clinical characteristics of dialysis patients with acute myocardial infarction in the United States: a collaborative project of the United States Renal Data System and the National Registry of Myocardial Infarction. Circulation. 2007;116:1465–72.

    Article 
    PubMed 

    Google Scholar
     

  • Fox CS, Muntner P, Chen AY, Alexander KP, Roe MT, Cannon CP, et al. Use of evidence-based therapies in short-term outcomes of ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in patients with chronic kidney disease: a report from the National Cardiovascular Data Acute Coronary Treatment and Intervention Outcomes Network registry. Circulation. 2010;121:357–65.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wanner C, Amann K, Shoji T. The heart and vascular system in dialysis. Lancet. 2016;388:276–84.

    Article 
    PubMed 

    Google Scholar
     

  • Kalantar-Zadeh K, Block G, Humphreys MH, Kopple JD. Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients. Kidney Int. 2003;63:793–808.

    Article 
    PubMed 

    Google Scholar
     

  • Malatino LS, Benedetto FA, Mallamaci F, Tripepi G, Zoccali C, Parlongo S, et al. Smoking, blood pressure and serum albumin are major determinants of carotid atherosclerosis in dialysis patients. CREED Investigators. Cardiovascular Risk Extended Evaluation in Dialysis patients. J Nephrol. 1999;12:256–60.

    CAS 
    PubMed 

    Google Scholar
     

  • Reiss AB, Voloshyna I, De Leon J, Miyawaki N, Mattana J. Cholesterol metabolism in CKD. Am J Kidney Dis. 2015;66:1071–82.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Shroff R, Speer T, Colin S, Charakida M, Zewinger S, Staels B, et al. HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype. J Am Soc Nephrol. 2014;25:2658–68.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zanoli L, Lentini P, Briet M, Castellino P, House AA, London GM, et al. Arterial stiffness in the heart disease of CKD. J Am Soc Nephrol. 2019;30:918–28.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zoccali C, Bode-Böger S, Mallamaci F, Benedetto F, Tripepi G, Malatino L, et al. Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study. Lancet. 2001;358:2113–7.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zoccali C, Mallamaci F, Maas R, Benedetto FA, Tripepi G, Malatino LS, et al. Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients. Kidney Int. 2002;62:339–45.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Testa A, Spoto B, Tripepi G, Mallamaci F, Malatino L, Fatuzzo P, et al. The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease. J Hypertens. 2005;23:1825–30.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Krediet RT, Balafa O. Cardiovascular risk in the peritoneal dialysis patient. Nat Rev Nephrol. 2010;6:451–60.

    Article 
    PubMed 

    Google Scholar
     

  • Bernardo AP, Oliveira JC, Santos O, Carvalho MJ, Cabrita A, Rodrigues A. Insulin resistance in nondiabetic peritoneal dialysis patients: associations with body composition, peritoneal transport, and peritoneal glucose absorption. Clin J Am Soc Nephrol. 2015;10:2205–12.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Nishimura M, Tsukamoto K, Tamaki N, Kikuchi K, Iwamoto N, Ono T. Risk stratification for cardiac death in hemodialysis patients without obstructive coronary artery disease. Kidney Int. 2011;79:363–71.

    Article 
    PubMed 

    Google Scholar
     

  • Radcliffe NJ, Seah J-M, Clarke M, MacIsaac RJ, Jerums G, Ekinci EI. Clinical predictive factors in diabetic kidney disease progression. J Diabetes Investig. 2017;8:6–18.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Nakashima A, Kato K, Ohkido I, Yokoo T. Role and treatment of insulin resistance in patients with chronic kidney disease: a review. Nutrients. 2021;13:4349.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mancusi C, de Simone G, Best LG, Wang W, Zhang Y, Roman MJ, et al. Myocardial mechano-energetic efficiency and insulin resistance in non-diabetic members of the Strong Heart Study cohort. Cardiovasc Diabetol. 2019;18:56.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hill MA, Yang Y, Zhang L, Sun Z, Jia G, Parrish AR, et al. Insulin resistance, cardiovascular stiffening and cardiovascular disease. Metabolism. 2021;119:154766.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6:299–304.

    Article 
    PubMed 

    Google Scholar
     

  • Demirci I, Haymana C, Candemir B, Meric C, Yuksel B, Eser M, et al. Triglyceride-glucose index levels in patients with congenital hypogonadotropic hypogonadism and the relationship with endothelial dysfunction and insulin resistance. Endokrynol Pol. 2021;72:232–7.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jiang Z-Z, Zhu J-B, Shen H-L, Zhao S-S, Tang Y-Y, Tang S-Q, et al. A high triglyceride-glucose index value is associated with an increased risk of carotid plaque burden in subjects with prediabetes and new-onset type 2 diabetes: a real-world study. Front Cardiovasc Med. 2022;9:832491.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mao Q, Zhou D, Li Y, Wang Y, Xu S-C, Zhao X-H. The triglyceride-glucose index predicts coronary artery disease severity and cardiovascular outcomes in patients with non-ST-segment elevation acute coronary syndrome. Dis Markers. 2019;2019:6891537.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhao J, Fan H, Wang T, Yu B, Mao S, Wang X, et al. TyG index is positively associated with risk of CHD and coronary atherosclerosis severity among NAFLD patients. Cardiovasc Diabetol. 2022;21:123.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Xiong S, Chen Q, Long Y, Su H, Luo Y, Liu H, et al. Association of the triglyceride-glucose index with coronary artery disease complexity in patients with acute coronary syndrome. Cardiovasc Diabetol. 2023;22:56.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang Y, Ding X, Hua B, Liu Q, Gao H, Chen H, et al. High triglyceride-glucose index is associated with adverse cardiovascular outcomes in patients with acute myocardial infarction. Nutr Metab Cardiovasc Dis. 2020;30:2351–62.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wu Z, Liu L, Wang W, Cui H, Zhang Y, Xu J, et al. Triglyceride-glucose index in the prediction of adverse cardiovascular events in patients with premature coronary artery disease: a retrospective cohort study. Cardiovasc Diabetol. 2022;21:142.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hu C, Zhang J, Liu J, Liu Y, Gao A, Zhu Y, et al. Discordance between the triglyceride glucose index and fasting plasma glucose or HbA1C in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study from China. Cardiovasc Diabetol. 2020;19:116.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 1983;51:606.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zoccali C, Benedetto FA, Maas R, Mallamaci F, Tripepi G, Salvatore Malatino L, et al. Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease. J Am Soc Nephrol. 2002;13:490–6.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Tripepi G, Mattace Raso F, Sijbrands E, Seck MS, Maas R, Boger R, et al. Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients. Clin J Am Soc Nephrol. 2011;6:1714–21.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Reaven G. Insulin resistance and coronary heart disease in nondiabetic individuals. Arterioscler Thromb Vasc Biol. 2012;32:1754–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Nerpin E, Risérus U, Ingelsson E, Sundström J, Jobs M, Larsson A, et al. Insulin sensitivity measured with euglycemic clamp is independently associated with glomerular filtration rate in a community-based cohort. Diabetes Care. 2008;31:1550–5.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Dave N, Wu J, Thomas S. Chronic kidney disease-induced insulin resistance: current state of the field. Curr Diab Rep. 2018;18:44.

    Article 
    PubMed 

    Google Scholar
     

  • Nishikawa T, Kukidome D, Sonoda K, Fujisawa K, Matsuhisa T, Motoshima H, et al. Impact of mitochondrial ROS production in the pathogenesis of insulin resistance. Diabetes Res Clin Pract. 2007;77(Suppl 1):S161-164.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Yang Q, Vijayakumar A, Kahn BB. Metabolites as regulators of insulin sensitivity and metabolism. Nat Rev Mol Cell Biol. 2018;19:654–72.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tao L-C, Xu J, Wang T, Hua F, Li J-J. Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations. Cardiovasc Diabetol. 2022;21:68.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Samuel VT, Shulman GI. The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. J Clin Invest. 2016;126:12–22.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jia G, DeMarco VG, Sowers JR. Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy. Nat Rev Endocrinol. 2016;12:144–53.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Cho Y-R, Ann SH, Won K-B, Park G-M, Kim Y-G, Yang DH, et al. Association between insulin resistance, hyperglycemia, and coronary artery disease according to the presence of diabetes. Sci Rep. 2019;9:6129.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Su J, Li Z, Huang M, Wang Y, Yang T, Ma M, et al. Triglyceride glucose index for the detection of the severity of coronary artery disease in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China. Cardiovasc Diabetol. 2022;21:96.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang X, Xu W, Song Q, Zhao Z, Meng X, Xia C, et al. Association between the triglyceride-glucose index and severity of coronary artery disease. Cardiovasc Diabetol. 2022;21:168.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jin J-L, Cao Y-X, Wu L-G, You X-D, Guo Y-L, Wu N-Q, et al. Triglyceride glucose index for predicting cardiovascular outcomes in patients with coronary artery disease. J Thorac Dis. 2018;10:6137–46.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     



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